Physiological and pathophysiological regulation of cytochrome P450

Edward T. Morgan, Marion B. Sewer, Heinrich Iber, Frank J. Gonzalez, Ying Hue Lee, Robert H. Tukey, Steve Okino, Tien Vu, Yue Hwa Chen, Jaspreet S. Sidhu, Curtis J. Omiecinski

研究成果: 雜誌貢獻文章

63 引文 斯高帕斯(Scopus)

摘要

This article is a report on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the April 1998 Experimental Biology '98 meeting in San Francisco. The presentations focused on the mechanisms of regulation of cytochrome P450 gene expression by developmental factors and by hormones and cytokines, as well as on the interplay between physiological and chemical regulation. Approaches and systems used to address these questions included conditional gene knockouts in mice, primary hepatocyte cultures, immunofluorescence imaging of cells, and cell lines stably expressing reporter gene constructs.

原文英語
頁(從 - 到)1232-1240
頁數9
期刊Drug Metabolism and Disposition
26
發行號12
出版狀態已發佈 - 1998
對外發佈Yes

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology

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