Photoproducts of naproxen in alcoholic solvents

Hsin Tsung Ho, An Bang Wu, Pen Yuan Lin, Jen Ai Lee, Pen Yueh Hung

研究成果: 書貢獻/報告類型章節


A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

主出版物標題Biomedical Chromatography
發行者Nova Science Publishers, Inc.
出版狀態已發佈 - 一月 1 2010

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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