Photochemical decomposition of alkannin/shikonin enantiomers

Hui Wen Cheng, Fu An Chen, Hsing Chu Hsu, Chau Yang Chen

研究成果: 雜誌貢獻文章同行評審

25 引文 斯高帕斯(Scopus)

摘要

Alkannin/shikonin ((±)-5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone), isolated from Macrotomia euchroma, is sensitive to light exposure. A chloroform solution of alkannin/shikonin was exposed to sunlight for 1 month. The major photolytic product, a newly discovered naphthoquinone derivative, was isolated by adsorption chromatography. The chemical structure of the purified photolytic product was identified by NMR, MS and FTIR techniques to be (-)-5,8-dihydroxy-2-(1-hydroxy-3-oxo-4-methyl-4-pentenyl)-1,4-naphthoquinone, indicating that a photo-oxidation reaction had occurred.

原文英語
頁(從 - 到)137-144
頁數8
期刊International Journal of Pharmaceutics
120
發行號2
DOIs
出版狀態已發佈 - 六月 30 1995

ASJC Scopus subject areas

  • Pharmaceutical Science

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