Perspective adjunctive therapies for COVID-19: Beyond antiviral therapy

Ping Ho, Jing Quan Zheng, Chia Chao Wu, Yi Chou Hou, Wen Chih Liu, Chien Lin Lu, Cai Mei Zheng, Kuo Cheng Lu, You Chen Chao

研究成果: 雜誌貢獻回顧型文獻同行評審

1 引文 斯高帕斯(Scopus)

摘要

The coronavirus disease 2019 (COVID-19) pandemic is the largest health crisis ever faced worldwide. It has resulted in great health and economic costs because no effective treatment is currently available. Since infected persons vary in presentation from healthy asymptomatic mild symptoms to those who need intensive care support and eventually succumb to the disease, this illness is considered to depend primarily on individual immunity. Demographic distribution and disease severity in several regions of the world vary; therefore, it is believed that natural inherent immunity provided through dietary sources and traditional medicines could play an important role in infection prevention and disease progression. People can boost their immunity to prevent them from infection after COVID-19 exposure and can reduce their inflammatory reactions to protect their organ deterioration in case suffering from the disease. Some drugs with in-situ immunomodulatory and anti-inflammatory activity are also identified as adjunctive therapy in the COVID-19 era. This review discusses the importance of COVID-19 interactions with immune cells and inflammatory cells; and further emphasizes the possible pathways related with traditional herbs, medications and nutritional products. We believe that such pathophysiological pathway approach treatment is rational and important for future development of new therapeutic agents for prevention or cure of COVID-19 infection.
原文英語
頁(從 - 到)314-324
頁數11
期刊International Journal of Medical Sciences
18
發行號2
DOIs
出版狀態已發佈 - 2021

ASJC Scopus subject areas

  • 醫藥 (全部)

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