Persistent leucocyte abnormalities in children years after previous long-term low-dose radiation exposure

Wushou P. Chang, Yi Ping Lin, Pai Tsang Hwang, Jih Luh Tang, Jer Yuan D Chen, Shy Dye Lee

研究成果: 雜誌貢獻文章同行評審

15 引文 斯高帕斯(Scopus)

摘要

Two hundred and eighty-nine children who had been educated in a kindergarten during 1983-92 and received continuous low-dose whole body gamma-irradiation from 60Co-contaminated steel window frames in their classrooms were investigated for residual effects on their haematological tissues. Another 751 children, sex and age-matched, received similar but much lower exposure in an elementary school with classrooms built with contaminated steel rebars. The peripheral leucocytes of these children were examined 5-7 years after they had stopped using these irradiated classrooms. Children who received higher exposure in the kindergarten were shown to have a significant decrease in total leucocytes and neutrophils and an increase in eosinophils. Moreover, they were shown to be at significantly higher risk of developing relative leucopenia and neutropenia, but not lymphocytopenia, than those who received a lower exposure at the elementary school. Children from the kindergarten who had much higher exposure were shown to have a significant lowering of total leucocytes and neutrophils, and an increase in eosinophils years after exposure. Residual adverse haematological effects on the exposed children are strongly suspected.

原文英語
頁(從 - 到)954-959
頁數6
期刊British Journal of Haematology
106
發行號4
DOIs
出版狀態已發佈 - 1999
對外發佈

ASJC Scopus subject areas

  • 血液學

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