Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission

研究成果: 雜誌貢獻文章

28 引文 斯高帕斯(Scopus)

摘要

Objective: A proinflammatory phase with various immunomodulatory mechanisms has been noted in bipolar mania and major depression. Weight gain and increased production of leptin may be associated with immunomodulation and insulin resistance in bipolar disorder. However, immunomodulation and its linkage with leptin and insulin in the depressive episode of bipolar disorder remain unclear. We investigated alterations in inflammatory markers and their relationship with leptin and insulin levels in patients with phases of bipolar disorder from acute depression to full remission. Methods: Thirty-two physically healthy bipolar I depressed patients aged
原文英語
頁(從 - 到)800-808
頁數9
期刊Bipolar Disorders
16
發行號8
DOIs
出版狀態已發佈 - 十二月 1 2014

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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