Peritoneal recurrence in serosa-negative gastric adenocarcinoma after curative surgery

Chun Chi Wu, Jen Hao Chen, Kuo Hung Huang, Wen Liang Fang, Chew Wun Wu, Su Shin Lo, Mao Chih Hsieh, King Han Shen, Anna Fen Yau Li

研究成果: 雜誌貢獻文章同行評審

摘要

Background/Aims: The rate of recurrence increases in proportion to the degree of tumor depth, even after curative resection for gastric adenocarcinoma. Serosal exposure is considered as an important risk factor of peritoneal recurrence. However, some patients with serosa-negative cancer were found to have peritoneal recurrence. There are few reports concerning risk factors of peritoneal recurrence in serosa-negative gastric adenocarcinoma. The aim of this study is to evaluate the incidence and risk factors of peritoneal recurrence in serosa-negative gastric adenocarcinoma after curative resection. Methodology: Total 1128 serosa-negative gastric cancer patients (574 pT1, 251 pT2, 303 pT3) diagnosed as gastric adenocarcinoma that underwent R0 resection from 1988 to 2005 were enrolled. Results: Peritoneal recurrence was observed in 50 (4.4%) patients, including 3 pT1, 3 pT2 and 44 pT3 patients. The incidence of peritoneal recurrence increased significantly with tumor invading subserosa (pT3). Multivariate analysis showed that the independent risk factor of peritoneal recurrence was tumor depth. Conclusions: The incidence of peritoneal recurrence in serosa-negative cancer is low, and tumor depth is a significant risk factor. We should be aware of peritoneal recurrence during follow-up, especially for patients with subserosal tumor invasion.
原文英語
頁(從 - 到)1119-1122
頁數4
期刊Hepato-Gastroenterology
58
發行號109
DOIs
出版狀態已發佈 - 七月 2011

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

指紋 深入研究「Peritoneal recurrence in serosa-negative gastric adenocarcinoma after curative surgery」主題。共同形成了獨特的指紋。

引用此