Patients with chronic periodontitis are more likely to develop upper urinary tract stone: A nation-wide populationbased eight-year follow up study

I. Shen Huang, Sung En Huang, Wei Tang Kao, Cheng Yen Chiang, To Chang, Cheng I. Lin, Alex T. Lin, Chih Chieh Lin, Yu Hua Fan, Hsiao Jen Chung

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

Background. The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. Methods. A total of 16,292 CP patients and 48,876 randomly-selected controls without chronic periodontitis were selected from the National research database and studied retrospectively. Subjects selected have not been diagnosed with UUTS previously. These subjects were prospectively followed for at least eight years. Cox regression models were used to explore the connection between risk factors and the development of UUTS. Results. The CP patients have a greater chance of developing UUTS compared to controls (1761/16292, 10.8% vs. 4775/48876, 9.8%, p-values < 0.001). Conditioned logistic regression suggested CP increases the risk of UUTS development (HR 1.14, 95% CI [1.08-1.20], p < 0.001). After respective adjustment for age, gender, hypertension and diabetes, results showed that CP still increases the risk of developing UUTS (HR 1.14, 95% CI [1.08-1.20], p < 0.001). Conclusion. By using a population-based database with a minimum eight 8 follow-up of CP in Taiwan, we discovered patients with CP are more likely to develop UUTS.

原文英語
文章編號e5287
期刊PeerJ
2018
發行號7
DOIs
出版狀態已發佈 - 一月 1 2018

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

指紋 深入研究「Patients with chronic periodontitis are more likely to develop upper urinary tract stone: A nation-wide populationbased eight-year follow up study」主題。共同形成了獨特的指紋。

引用此