Parallel alignment of bacteria using near-field optical force array for cell sorting

H. T. Zhao, Y. Zhang, L. K. Chin, P. H. Yap, K. Wang, W. Ser, A. Q. Liu

研究成果: 書貢獻/報告類型會議貢獻

摘要

This paper presents a near-field approach to align multiple rod-shaped bacteria based on the interference pattern in silicon nano-waveguide arrays. The bacteria in the optical field will be first trapped by the gradient force and then rotated by the scattering force to the equilibrium position. In the experiment, the Shigella bacteria is rotated 90 deg and aligned to horizontal direction in 9.4 s. Meanwhile, ∼150 Shigella is trapped on the surface in 5 min and 86% is aligned with angle <; 5 deg. This method is a promising toolbox for the research of parallel single-cell biophysical characterization, cell-cell interaction, etc.
原文英語
主出版物標題Optical Trapping and Optical Micromanipulation XIV
編輯Gabriel C. Spalding, Kishan Dholakia
發行者SPIE
ISBN(電子)9781510611511
DOIs
出版狀態已發佈 - 一月 1 2017
事件Optical Trapping and Optical Micromanipulation XIV 2017 - San Diego, 美国
持續時間: 八月 6 2017八月 10 2017

出版系列

名字Proceedings of SPIE - The International Society for Optical Engineering
10347
ISSN(列印)0277-786X
ISSN(電子)1996-756X

會議

會議Optical Trapping and Optical Micromanipulation XIV 2017
國家美国
城市San Diego
期間8/6/178/10/17

    指紋

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

引用此

Zhao, H. T., Zhang, Y., Chin, L. K., Yap, P. H., Wang, K., Ser, W., & Liu, A. Q. (2017). Parallel alignment of bacteria using near-field optical force array for cell sorting. 於 G. C. Spalding, & K. Dholakia (編輯), Optical Trapping and Optical Micromanipulation XIV [1034739] (Proceedings of SPIE - The International Society for Optical Engineering; 卷 10347). SPIE. https://doi.org/10.1117/12.2271939