Outcome of treatment with total main tumor resection and supraomohyoid neck dissection in oral squamous cell carcinoma

Gwo An Liaw, Ching Yu Yen, Wei Fan Chiang, Chin Hai Lee, Cheng Yang, Chang Ta Chiou, Shyun Yeu Liu

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Background/Purpose: Supraomohyoid neck dissection (SOHND) is commonly used to treat oral squamous cell carcinoma (OSCC) patients with clinical N0 or selected N1 status. The purpose of this study was to evaluate the clinical outcome of OSCC patients treated with SOHND. Methods: This retrospective study reviewed the clinical outcome of 257 patients (247 men, 10 women) with NO, N1 and N2a OSCC treated with wide excision of the main tumor and SOHND between 1992 and 1999. All patients were followed up for at least 5 years. Survival distributions were analyzed using Kaplan-Meier curves. N status was compared using x2 and log rank tests. Results: The neck failure rate was 20% for clinically false negative cases, 6.1% for clinically true negative cases, 21.8% for clinically false positive cases, and 40% for clinically true positive cases. The 3- and 5-year overall neck disease-free survival rates were 79.8% and 77.6%, respectively. The 3- and 5-year neck disease-free survival rates were 86.7% and 84.2% for pathologic N0 cases, 56.9% and 56.9% for pathologic N1 cases, and 27.5% and 27.5% for pathologic N2 cases, respectively. Log rank test showed that the p value for difference in survival at 3-5 years was 0.064 for pathologic N0 vs. N1 cases,
原文英語
頁(從 - 到)971-977
頁數7
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
105
發行號12
出版狀態已發佈 - 十二月 2006

ASJC Scopus subject areas

  • 醫藥 (全部)

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