Organic carbon and acidic ions in PM2.5 contributed to particle bioreactivity in Chinese megacities during haze episodes

Kin Fai Ho, Ya Chun Lee, Xinyi Niu, Hongmei Xu, Renjian Zhang, Jun Ji Cao, Cheng Yu Tsai, Ta Chih Hsiao, Hsiao Chi Chuang

研究成果: 雜誌貢獻文章同行評審

摘要

Fine particulate matter (PM2.5) has been linked to cardiopulmonary disease and systemic effects in humans. However, few studies have investigated the particle bioreactivity in Chinese megacities during haze episodes. The objective of this study was to determine the contributions of chemical components in PM2.5 to particle bioreactivity in Chinese megacities during haze episodes. PM2.5 samples were collected in 14 megacities across China from 23 December 2013 to 16 January 2014. Average PM2.5 concentrations ranged 88.92~199.67 μg/m3. Organic carbon (OC), elemental carbon (EC), anions, and cations per unit of PM2.5 were linked to cellular bioreactivity (i.e., reactive oxygen species (ROS) as assessed by dichlorodihydrofluorescein diacetate (DCFH) and inflammation as assessed by interleukin (IL)-6 in A549 cells). The contributions of chemicals in PM2.5 to ROS and inflammation were examined by the Pearson correlation coefficient and random forests. These results indicated that OC, Ca2+, SO42−, Cl−, F−, K+, and NO3− contributed to ROS production, whereas OC, Cl−, EC, K+, F−, Na+, and Ca2+ contributed to inflammation. In conclusion, PM2.5-contained OC and acidic ions are important in regulation of oxidative stress and inflammation during haze episodes. Our findings suggest that severe haze PM2.5 events cause deterioration in air quality and may adversely affect human health.
原文英語
頁(從 - 到)11865-11873
頁數9
期刊Environmental Science and Pollution Research
29
發行號8
DOIs
出版狀態已發佈 - 2月 2022

ASJC Scopus subject areas

  • 環境化學
  • 污染
  • 健康、毒理學和誘變

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