Background: Optic neuritis in herpes zoster ophthalmicus (HZO) has been reported rarely. We report two cases of HZO optic neuritis with detailed magnetic resonance imaging study and treatment responses. Cases: One patient presented with anterior optic nerve involvement, and the second presented with retrobulbar optic neuritis. Contrast enhanced T1-weighted images were obtained in these 2 patients. Intravenous acyclovir and oral prednisolone were given simultaneously. Observations: Magnetic resonance imaging revealed peripheral enhancement of the optic nerve sheath complex on T1-weighted scan. Both patients recovered their vision within 3 months following the start of treatment. Conclusions: Magnetic resonance imaging is helpful for the diagnosis of HZO optic neuritis. Systemic acyclovir and steroid are effective in the treatment of HZO optic neuritis. (C) 2000 Japanese Ophthalmological Society.
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