49 引文 (Scopus)

摘要

Study Objectives: Empirical findings on the prospective link between obstructive sleep apnea (OSA) and subsequent depression are mixed. This nationwide, population-based study thus aimed at assessing the risk of depressive disorder within the first year following a diagnosis with OSA. Gender effects were further examined. Design: Cohort study. Setting: Taiwan. Patients: This study used data from the Longitudinal Health Insurance Database 2000. A total of 2,818 patients diagnosed with OSA between 2002 and 2008 were evaluated, and 14,090 matched non-OSA enrollees used as a comparison cohort. Measurements and Results: Each patient was followed for one year to identify subsequent depressive disorder. We found that during the one-year follow-up, the incidence of depressive disorder per thousand person-years was about twice as high among patients with OSA (18.10, 95% CI = 13.62-23.61) as those without OSA (8.23, 95% CI = 6.83-9.84). The Cox proportional hazards model revealed that patients with OSA were independently associated with a 2.18 times (95% CI = 1.55-3.08) increased risk of subsequent depressive disorder within a year, compared to those without OSA. As epidemiological studies have consistently documented an increased risk for depression in women, we hypothesized and confirmed higher risks of depressive disorder among female patients with OSA (2.72, 95% CI = 1.68-4.40) than their male counterparts (1.81, 95% CI = 1.09-3.01). Conclusion: A prospective link between OSA and subsequent depressive disorder within one year was confirmed by the current study. The risk was particularly evident among women. Regular psychiatric screening among patients with OSA is suggested to prompt the timely detection of depression.
原文英語
頁(從 - 到)417-423
頁數7
期刊Journal of Clinical Sleep Medicine
9
發行號5
DOIs
出版狀態已發佈 - 五月 15 2013

指紋

Obstructive Sleep Apnea
Depressive Disorder
Population
Depression
Sleep Apnea Syndromes
Health Insurance
Taiwan
Proportional Hazards Models
Psychiatry
Epidemiologic Studies
Cohort Studies
Databases
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Pulmonary and Respiratory Medicine
  • Neurology

引用此文

@article{246d0e13a6de4ea38c396fbd81c2de67,
title = "Obstructive sleep apnea and the subsequent risk of depressive disorder: A population-based follow-up study",
abstract = "Study Objectives: Empirical findings on the prospective link between obstructive sleep apnea (OSA) and subsequent depression are mixed. This nationwide, population-based study thus aimed at assessing the risk of depressive disorder within the first year following a diagnosis with OSA. Gender effects were further examined. Design: Cohort study. Setting: Taiwan. Patients: This study used data from the Longitudinal Health Insurance Database 2000. A total of 2,818 patients diagnosed with OSA between 2002 and 2008 were evaluated, and 14,090 matched non-OSA enrollees used as a comparison cohort. Measurements and Results: Each patient was followed for one year to identify subsequent depressive disorder. We found that during the one-year follow-up, the incidence of depressive disorder per thousand person-years was about twice as high among patients with OSA (18.10, 95{\%} CI = 13.62-23.61) as those without OSA (8.23, 95{\%} CI = 6.83-9.84). The Cox proportional hazards model revealed that patients with OSA were independently associated with a 2.18 times (95{\%} CI = 1.55-3.08) increased risk of subsequent depressive disorder within a year, compared to those without OSA. As epidemiological studies have consistently documented an increased risk for depression in women, we hypothesized and confirmed higher risks of depressive disorder among female patients with OSA (2.72, 95{\%} CI = 1.68-4.40) than their male counterparts (1.81, 95{\%} CI = 1.09-3.01). Conclusion: A prospective link between OSA and subsequent depressive disorder within one year was confirmed by the current study. The risk was particularly evident among women. Regular psychiatric screening among patients with OSA is suggested to prompt the timely detection of depression.",
keywords = "Depressive disorder, Obstructive sleep apnea, Prospective link",
author = "Chen, {Yi Hua} and Keller, {Joseph K.} and Kang, {Jiunn Horng} and Hsieh, {Heng Ju} and Lin, {Herng Ching}",
year = "2013",
month = "5",
day = "15",
doi = "10.5664/jcsm.2652",
language = "English",
volume = "9",
pages = "417--423",
journal = "Journal of Clinical Sleep Medicine",
issn = "1550-9389",
publisher = "American Academy of Sleep Medicine",
number = "5",

}

TY - JOUR

T1 - Obstructive sleep apnea and the subsequent risk of depressive disorder

T2 - A population-based follow-up study

AU - Chen, Yi Hua

AU - Keller, Joseph K.

AU - Kang, Jiunn Horng

AU - Hsieh, Heng Ju

AU - Lin, Herng Ching

PY - 2013/5/15

Y1 - 2013/5/15

N2 - Study Objectives: Empirical findings on the prospective link between obstructive sleep apnea (OSA) and subsequent depression are mixed. This nationwide, population-based study thus aimed at assessing the risk of depressive disorder within the first year following a diagnosis with OSA. Gender effects were further examined. Design: Cohort study. Setting: Taiwan. Patients: This study used data from the Longitudinal Health Insurance Database 2000. A total of 2,818 patients diagnosed with OSA between 2002 and 2008 were evaluated, and 14,090 matched non-OSA enrollees used as a comparison cohort. Measurements and Results: Each patient was followed for one year to identify subsequent depressive disorder. We found that during the one-year follow-up, the incidence of depressive disorder per thousand person-years was about twice as high among patients with OSA (18.10, 95% CI = 13.62-23.61) as those without OSA (8.23, 95% CI = 6.83-9.84). The Cox proportional hazards model revealed that patients with OSA were independently associated with a 2.18 times (95% CI = 1.55-3.08) increased risk of subsequent depressive disorder within a year, compared to those without OSA. As epidemiological studies have consistently documented an increased risk for depression in women, we hypothesized and confirmed higher risks of depressive disorder among female patients with OSA (2.72, 95% CI = 1.68-4.40) than their male counterparts (1.81, 95% CI = 1.09-3.01). Conclusion: A prospective link between OSA and subsequent depressive disorder within one year was confirmed by the current study. The risk was particularly evident among women. Regular psychiatric screening among patients with OSA is suggested to prompt the timely detection of depression.

AB - Study Objectives: Empirical findings on the prospective link between obstructive sleep apnea (OSA) and subsequent depression are mixed. This nationwide, population-based study thus aimed at assessing the risk of depressive disorder within the first year following a diagnosis with OSA. Gender effects were further examined. Design: Cohort study. Setting: Taiwan. Patients: This study used data from the Longitudinal Health Insurance Database 2000. A total of 2,818 patients diagnosed with OSA between 2002 and 2008 were evaluated, and 14,090 matched non-OSA enrollees used as a comparison cohort. Measurements and Results: Each patient was followed for one year to identify subsequent depressive disorder. We found that during the one-year follow-up, the incidence of depressive disorder per thousand person-years was about twice as high among patients with OSA (18.10, 95% CI = 13.62-23.61) as those without OSA (8.23, 95% CI = 6.83-9.84). The Cox proportional hazards model revealed that patients with OSA were independently associated with a 2.18 times (95% CI = 1.55-3.08) increased risk of subsequent depressive disorder within a year, compared to those without OSA. As epidemiological studies have consistently documented an increased risk for depression in women, we hypothesized and confirmed higher risks of depressive disorder among female patients with OSA (2.72, 95% CI = 1.68-4.40) than their male counterparts (1.81, 95% CI = 1.09-3.01). Conclusion: A prospective link between OSA and subsequent depressive disorder within one year was confirmed by the current study. The risk was particularly evident among women. Regular psychiatric screening among patients with OSA is suggested to prompt the timely detection of depression.

KW - Depressive disorder

KW - Obstructive sleep apnea

KW - Prospective link

UR - http://www.scopus.com/inward/record.url?scp=84877968582&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877968582&partnerID=8YFLogxK

U2 - 10.5664/jcsm.2652

DO - 10.5664/jcsm.2652

M3 - Article

C2 - 23674930

AN - SCOPUS:84877968582

VL - 9

SP - 417

EP - 423

JO - Journal of Clinical Sleep Medicine

JF - Journal of Clinical Sleep Medicine

SN - 1550-9389

IS - 5

ER -