Novel terpenoids from Calocedrus macrolepis var. formosana

Chin Lin Hsieh, Mei Hwei Tseng, Ryh Nan Pan, Jang Yang Chang, Ching Chuan Kuo, Zong-Huei Li, Yueh Hsiung Kuo

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Calocetriol (1), diacetylcalocediol (2), and ferrugimenthenol (3) were isolated from the bark of Calocedrus macrolepis var. formosana. Among them, 1 and 2 are secoabietane-type diterpenoids, and 3, with a novel C 20-C 10 skeleton, is classified as a meroterpenoid. The structures of 1-3 were elucidated by spectroscopic analyses, and their biological activities were also evaluated. Compound 3 exhibited significant cytotoxic activity against human oral epidermoid carcinoma KB cells with an IC 50 value of 9.0±0.1 μM.
原文英語
頁(從 - 到)1901-1907
頁數7
期刊Chemistry and Biodiversity
8
發行號10
DOIs
出版狀態已發佈 - 十月 2011

ASJC Scopus subject areas

  • 生物化學
  • 化學 (全部)
  • 生物工程
  • 分子生物學
  • 分子醫學

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