Novel SNPs in a candidate gene, CRTH2, for allergic diseases

S. C. Hsu, L. C. Chen, M. L. Kuo, J. Long Huang, S. K. Huang

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)


Sequencing analyses of genomic DNA samples from a Chinese population identified four single-nucleotide polymorphisms (SNPs) of the CRTH2 gene, encoding a chemoattractant receptor predominantly expressed on Th2 cells and a receptor for prostaglandin D2 (PGD2). Two coding-region SNPs with a T to G and a C to A substitutions, resulting in codon changes from Phe to Val and Pro to Thr, respectively. Two additional SNPs were discovered in the 3′ untranslated region (3′-UTR). These newly identified SNPs will be useful for further functional study of variant CRTH2 gene, and for genetic studies of asthma and other immunologic diseases.

頁(從 - 到)114-116
期刊Genes and Immunity
出版狀態已發佈 - 四月 1 2002

ASJC Scopus subject areas

  • Genetics(clinical)
  • Immunology
  • Genetics

指紋 深入研究「Novel SNPs in a candidate gene, CRTH2, for allergic diseases」主題。共同形成了獨特的指紋。

  • 引用此