摘要
Two chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG1 and HMG2, reduce the linking number (topological winding number) of a circular DNA if the covalent closure of the DNA is carried out in their presence. This indicates that these proteins can either unwind the double helix, or induce a supercoiling of the DNA.
原文 | 英語 |
---|---|
頁(從 - 到) | 1345-1346 |
頁數 | 2 |
期刊 | Science |
卷 | 199 |
發行號 | 4335 |
出版狀態 | 已發佈 - 1978 |
對外發佈 | Yes |
ASJC Scopus subject areas
- General