Nonhistone proteins HMG1 and HMG2 change the DNA helical structure

Kashayar Javaherian, Leroy-Fong Liu, James C. Wang

研究成果: 雜誌貢獻 › 文章

173 引文 斯高帕斯（Scopus）

摘要

Two chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG1 and HMG2, reduce the linking number (topological winding number) of a circular DNA if the covalent closure of the DNA is carried out in their presence. This indicates that these proteins can either unwind the double helix, or induce a supercoiling of the DNA.

原文英語
頁（從 - 到）1345-1346
頁數2
期刊Science
卷199
發行號4335
出版狀態已發佈 - 1978
對外發佈Yes

ASJC Scopus subject areas

  • General

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    Javaherian, K., Liu, L-F., & Wang, J. C. (1978). Nonhistone proteins HMG1 and HMG2 change the DNA helical structure. Science, 199(4335), 1345-1346.