No mutation of G209A in the alpha-synuclein gene in sporadic Parkinson's disease among Taiwan Chinese

Chaur Jong Hu, Shing Ming Sung, Hsing Cheng Liu, Jan Gowth Chang

研究成果: 雜誌貢獻文章同行評審

19 引文 斯高帕斯(Scopus)

摘要

The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the α-synuclein gene has been identified in cases of familial PD. We looked for this mutation in 65 cases of sporadic PD in Taiwan Chinese patients but found none of these patients with this mutation. We conclude that mutation of G209A in the α-synuclein gene plays no role in sporadic PD among Taiwan Chinese.

原文英語
頁(從 - 到)85-87
頁數3
期刊European Neurology
41
發行號2
DOIs
出版狀態已發佈 - 二月 1999
對外發佈

ASJC Scopus subject areas

  • 神經病學(臨床)

指紋

深入研究「No mutation of G209A in the alpha-synuclein gene in sporadic Parkinson's disease among Taiwan Chinese」主題。共同形成了獨特的指紋。

引用此