No association of alpha-2 macroglobulin gene five-nucleotide deletion with AD in Taiwan Chinese

C. J. Hu, S. M. Sung, H. C. Liu, K. Y. Lee, W. C. Hsu, W. K. Wong, C. C. Lee, C. H. Tsai, Jan Gowth Chang

研究成果: 雜誌貢獻文章同行評審

22 引文 斯高帕斯(Scopus)

摘要

The alpha-2 macroglobulin five-nucleotide deletion (A2M-2) allele frequency was not significantly higher in the AD group than the control group (0.062 versus 0.101, p > 0.1). The odds ratio for AD in individuals with the A2M-2 allele was 0.582 (95% CI, 0.25 to 1.40). These results do not support the association between A2M-2 and AD in the Chinese population, although the allele frequency of A2M-2 is lower than that found in the Caucasian population. Therefore, A2M-2 might not be a significant risk factor of AD among Taiwan Chinese.

原文英語
頁(從 - 到)642-643
頁數2
期刊Neurology
53
發行號3
DOIs
出版狀態已發佈 - 八月 11 1999
對外發佈

ASJC Scopus subject areas

  • 神經病學(臨床)

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