New abietane-type diterpenoids from the bark of cryptomeria japonica

Chi I. Chang, Jih Jung Chen, Chin Hsu, Cheng Chi Chen, Wei Yi Cheng, Sheng Yang Wang, Ching Kuo Lee, Ming Jen Cheng, Yueh Hsiung Kuo

研究成果: 雜誌貢獻文章

摘要

Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.

原文英語
頁(從 - 到)97-100
頁數4
期刊Natural Product Communications
14
發行號1
DOIs
出版狀態已發佈 - 一月 1 2019

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

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  • 引用此

    Chang, C. I., Chen, J. J., Hsu, C., Chen, C. C., Cheng, W. Y., Wang, S. Y., Lee, C. K., Cheng, M. J., & Kuo, Y. H. (2019). New abietane-type diterpenoids from the bark of cryptomeria japonica. Natural Product Communications, 14(1), 97-100. https://doi.org/10.1177/1934578X1901400125