New abietane-type diterpenoids from the bark of cryptomeria japonica

Chi I. Chang; Jih Jung Chen; Chin Hsu; Cheng Chi Chen; Wei Yi Cheng; Sheng Yang Wang; Ching Kuo Lee; Ming Jen Cheng; Yueh Hsiung Kuo

doi:10.1177/1934578X1901400125

New abietane-type diterpenoids from the bark of cryptomeria japonica

Chi I. Chang, Jih Jung Chen, Chin Hsu, Cheng Chi Chen, Wei Yi Cheng, Sheng Yang Wang, Ching Kuo Lee, Ming Jen Cheng, Yueh Hsiung Kuo

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

摘要

Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.

原文	英語
頁（從 - 到）	97-100
頁數	4
期刊	Natural Product Communications
卷	14
發行號	1
DOIs	https://doi.org/10.1177/1934578X1901400125
出版狀態	已發佈 - 1月 1 2019

ASJC Scopus subject areas

藥理
藥物發現
植物科學
補充和替代醫學

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10.1177/1934578X1901400125

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abstract = "Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.",

keywords = "Abietane, Cryptomeria japonica, Cupressaceae, Diterpenoid, Traditional herbal medicine",

author = "Chang, {Chi I.} and Chen, {Jih Jung} and Chin Hsu and Chen, {Cheng Chi} and Cheng, {Wei Yi} and Wang, {Sheng Yang} and Lee, {Ching Kuo} and Cheng, {Ming Jen} and Kuo, {Yueh Hsiung}",

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AU - Chang, Chi I.

AU - Chen, Jih Jung

AU - Hsu, Chin

AU - Chen, Cheng Chi

AU - Cheng, Wei Yi

AU - Wang, Sheng Yang

AU - Lee, Ching Kuo

AU - Cheng, Ming Jen

AU - Kuo, Yueh Hsiung

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.

AB - Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.

KW - Abietane

KW - Cryptomeria japonica

KW - Cupressaceae

KW - Diterpenoid

KW - Traditional herbal medicine

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JO - Natural Product Communications

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ER -

New abietane-type diterpenoids from the bark of cryptomeria japonica

摘要

ASJC Scopus subject areas

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