New abietane-type diterpenoids from the bark of cryptomeria japonica

Chi I. Chang, Jih Jung Chen, Chin Hsu, Cheng Chi Chen, Wei Yi Cheng, Sheng Yang Wang, Ching Kuo Lee, Ming Jen Cheng, Yueh Hsiung Kuo

研究成果: 雜誌貢獻文章

摘要

Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2?-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM.

原文英語
頁(從 - 到)97-100
頁數4
期刊Natural Product Communications
14
發行號1
DOIs
出版狀態已發佈 - 一月 1 2019

指紋

Abietane Diterpenes
Cryptomeria
xanthine oxidase
Cryptomeria japonica
Xanthine Oxidase
Diterpenes
diterpenoids
Methanol
bark
methanol
extracts
Enzymes
enzymes

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

引用此文

Chang, C. I., Chen, J. J., Hsu, C., Chen, C. C., Cheng, W. Y., Wang, S. Y., ... Kuo, Y. H. (2019). New abietane-type diterpenoids from the bark of cryptomeria japonica. Natural Product Communications, 14(1), 97-100. https://doi.org/10.1177/1934578X1901400125

New abietane-type diterpenoids from the bark of cryptomeria japonica. / Chang, Chi I.; Chen, Jih Jung; Hsu, Chin; Chen, Cheng Chi; Cheng, Wei Yi; Wang, Sheng Yang; Lee, Ching Kuo; Cheng, Ming Jen; Kuo, Yueh Hsiung.

於: Natural Product Communications, 卷 14, 編號 1, 01.01.2019, p. 97-100.

研究成果: 雜誌貢獻文章

Chang, CI, Chen, JJ, Hsu, C, Chen, CC, Cheng, WY, Wang, SY, Lee, CK, Cheng, MJ & Kuo, YH 2019, 'New abietane-type diterpenoids from the bark of cryptomeria japonica', Natural Product Communications, 卷 14, 編號 1, 頁 97-100. https://doi.org/10.1177/1934578X1901400125
Chang, Chi I. ; Chen, Jih Jung ; Hsu, Chin ; Chen, Cheng Chi ; Cheng, Wei Yi ; Wang, Sheng Yang ; Lee, Ching Kuo ; Cheng, Ming Jen ; Kuo, Yueh Hsiung. / New abietane-type diterpenoids from the bark of cryptomeria japonica. 於: Natural Product Communications. 2019 ; 卷 14, 編號 1. 頁 97-100.
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