Neurobiologische grundlagen depressiver syndrome

Christian Stoppel, H. Bielau, B. Bogerts, G. Northoff

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Depressive disorders belong to the most frequent diseases worldwide showing a lifetime prevalence of up to 20%. Moreover they are one of the leading causes for the amount of years lived with disability. Increasing knowledge about the pathological mechanisms underlying depressive syndromes is obtained by using modern neurobiological research-techniques. Thereby some older theories that have been the basis of emotion-research for decades - like the monoamine hypothesis - have been strengthened. In addition new aspects of the pathological processes underlying depressive disturbances have been unraveled. In this review established models and recent findings will be discussed, to bridge various research-fields, ranging from genetics, epigenetics and morphological changes to the functional consequences of depression. Finally therapeutic implications that could be derived from these results will be presented, showing up putative possibilities for diagnosis and treatment of depressive syndromes.
貢獻的翻譯標題Neurobiological basis of depressive disorders
原文德語
頁(從 - 到)696-705
頁數10
期刊Fortschritte der Neurologie Psychiatrie
74
發行號12
DOIs
出版狀態已發佈 - 12月 2006
對外發佈

ASJC Scopus subject areas

  • 神經病學(臨床)
  • 神經內科
  • 精神病學和心理健康

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