Necrotizing pneumococcal pneumonia in children: The role of pulmonary gangrene

Yu Chia Hsieh, Cheng Hsiang Hsiao, Po Nien Tsao, Jann Yuan Wang, Po Ren Hsueh, Bor Luen Chiang, Wen Sen Lee, Li Min Huang

研究成果: 雜誌貢獻文章

44 引文 (Scopus)

摘要

Little is known about the mechanism of necrotizing pneumonia caused by Streptococcus pneumoniae in children. Pulmonary gangrene secondary to vascular thrombosis was reported in adults with necrotizing pneumococcal pneumonia. We conducted a retrospective study of 15 children with a diagnosis of necrotizing pneumococcal pneumonia at National Taiwan University Hospital to explore its association with pulmonary gangrene, based on evidence from chest computed tomography, serial chest radiographic patterns, and pathologic results. S. pneumoniae serotype 14 was the prevalent pneumococcal serotype. Overall, 63.6% of isolates were not susceptible to penicillin. One child with pneumonia caused by S. pneumoniae serotype 3 complicated by hemolytic uremic syndrome had a rapidly fatal course. An autopsy in this patient documented lung necrosis and pulmonary gangrene. Radiographic follow-up was performed during the clinical course in 9 patients, and showed no evidence of pulmonary gangrene. Four children had no radiographic follow-up. The relationship between pulmonary gangrene and necrotizing pneumonia was unclear in the remaining one. In conclusion, necrotizing pneumococcal pneumonia may be infrequently associated with pulmonary gangrene in children.
原文英語
頁(從 - 到)623-629
頁數7
期刊Pediatric Pulmonology
41
發行號7
DOIs
出版狀態已發佈 - 七月 2006

指紋

Pneumococcal Pneumonia
Gangrene
Lung
Streptococcus pneumoniae
Thorax
Hemolytic-Uremic Syndrome
Necrotizing Pneumonia
Taiwan
Penicillins
Blood Vessels
Autopsy
Pneumonia
Thrombosis
Necrosis
Retrospective Studies
Tomography

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

引用此文

Hsieh, Y. C., Hsiao, C. H., Tsao, P. N., Wang, J. Y., Hsueh, P. R., Chiang, B. L., ... Huang, L. M. (2006). Necrotizing pneumococcal pneumonia in children: The role of pulmonary gangrene. Pediatric Pulmonology, 41(7), 623-629. https://doi.org/10.1002/ppul.20411

Necrotizing pneumococcal pneumonia in children : The role of pulmonary gangrene. / Hsieh, Yu Chia; Hsiao, Cheng Hsiang; Tsao, Po Nien; Wang, Jann Yuan; Hsueh, Po Ren; Chiang, Bor Luen; Lee, Wen Sen; Huang, Li Min.

於: Pediatric Pulmonology, 卷 41, 編號 7, 07.2006, p. 623-629.

研究成果: 雜誌貢獻文章

Hsieh, YC, Hsiao, CH, Tsao, PN, Wang, JY, Hsueh, PR, Chiang, BL, Lee, WS & Huang, LM 2006, 'Necrotizing pneumococcal pneumonia in children: The role of pulmonary gangrene', Pediatric Pulmonology, 卷 41, 編號 7, 頁 623-629. https://doi.org/10.1002/ppul.20411
Hsieh YC, Hsiao CH, Tsao PN, Wang JY, Hsueh PR, Chiang BL 等. Necrotizing pneumococcal pneumonia in children: The role of pulmonary gangrene. Pediatric Pulmonology. 2006 7月;41(7):623-629. https://doi.org/10.1002/ppul.20411
Hsieh, Yu Chia ; Hsiao, Cheng Hsiang ; Tsao, Po Nien ; Wang, Jann Yuan ; Hsueh, Po Ren ; Chiang, Bor Luen ; Lee, Wen Sen ; Huang, Li Min. / Necrotizing pneumococcal pneumonia in children : The role of pulmonary gangrene. 於: Pediatric Pulmonology. 2006 ; 卷 41, 編號 7. 頁 623-629.
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