Near-infrared bone densitometry: A feasibility study on distal radius measurement

Chun Chung, Yu Pin Chen, Tsai Hsueh Leu, Chia Wei Sun

研究成果: 雜誌貢獻快報同行評審

1 引文 斯高帕斯(Scopus)

摘要

Osteoporosis, defined as decreased bone mineral density (BMD), poses patients in dangers for fracture risk and has become a major public health problem worldwide because of is associated morbidity, mortality and costs. Without doubt, early detection and timely intervention are important to successfully manage osteoporosis and its associated complications. The dual-energy x-ray absorptiometry (DXA) is the most popular and standard method to measure BMD. However, limitations including radiation exposure and availability restrict its application for osteoporosis screening among general population. In this study, we developed a simple method to detect human distal radius bone density based on near infrared (NIR) image system. Among 10 volunteers (including 5 young and 5 elderly participants) receiving bone density measurement using our NIR image system at the ultradistal part of bilateral distal radius, we demonstrated a strong correlation between the optical attenuation and BMD measured with DXA, which may facilitate predicting bone density status. We hope our potential NIR image system may open a new avenue for development of osteoporosis screening facilities and help in prevention of osteoporosis related fracture and its associated complications in the near future. Pearson's correlations between BMD values from the DXA and light intensity of NIR system.

原文英語
文章編號e201700342
期刊Journal of Biophotonics
11
發行號7
DOIs
出版狀態已發佈 - 七月 2018

ASJC Scopus subject areas

  • 化學 (全部)
  • 材料科學(全部)
  • 生物化學、遺傳與分子生物學 (全部)
  • 工程 (全部)
  • 物理與天文學 (全部)

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