Natural-synthetic polyblend nanofibers for biomedical applications

Narayan Bhattarai, Zhensheng Li, Jonathan Gunn, Matthew Leung, Ashleigh Cooper, Dennis Edmondson, Omid Veiseh, Ming Hong Chen, Yong Zhang, Richard G. Ellenbogen, Miqin Zhang

研究成果: 雜誌貢獻文章同行評審

135 引文 斯高帕斯(Scopus)

摘要

The development and characterization of a natural-synthetic polymeric nanofiber comprised of well-blended chitosan and poly(caprolactone) (PCL) is discussed. The design combined the technological advancements in biocompatible polymers and nanotechnology to produce nanofibrous matrices with significantly improved mechanical and biological properties. The well-blended chitosan-PCL nanofibrous matrix integrated the favorable biological properties of chitosan and mechanical properties, while providing a stable and favorable environment for a wide range of biomedical applications. A conduit was constructed from the nanofiber as a model biomedical engineering application for potential nerve regeneration and investigate mechanical and biological properties in vitro. The specific application was studied as it represented a challenge and needed significant requirements in material's mechanical and biological properties among tissue engineering applications.
原文英語
頁(從 - 到)2792-2797
頁數6
期刊Advanced Materials
21
發行號27
DOIs
出版狀態已發佈 - 7月 20 2009
對外發佈

ASJC Scopus subject areas

  • 材料科學(全部)
  • 材料力學
  • 機械工業

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