Nasal Rosai-Dorfman disease with intracranial involvement: A case report

Yu Chien Chang, Ming Hsui Tsai, Chi Long Chen, Chon Haw Tsai, Alex Ying Shyuan Lee

研究成果: 雜誌貢獻文章同行評審

13 引文 斯高帕斯(Scopus)


Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare but distinctive entity. It was initially described as a nodal-based disease but later found to affect a variety of extranodal sites. The diagnosis of Rosai-Dorfman disease is based on the unique histologic changes that are characterized by proliferation of S-100 protein-positive histiocytes, the presence of emperipolesis, and a mixture of prominent lymphoplasmacytic infiltrates. The etiology of Rosai-Dorfman disease is unknown. It usually runs a benign clinic course and may resolve spontaneously, but cases running protracted courses have also been reported. We report an unusual case of recurrent extranodal Rosai-Dorfman disease in nasal and paranasal cavities with intracranial involvement surviving for more than 9 years.

頁(從 - 到)183-186
期刊American Journal of Otolaryngology - Head and Neck Medicine and Surgery
出版狀態已發佈 - 5月 2003

ASJC Scopus subject areas

  • 耳鼻咽喉科


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