Nanowire field effect transistor with its sub-picomolar label-free biosensing capability toward a gene mutation

Chi Chang Wu, Fu Hsiang Ko, Ting Siang Su, Bo Syuan Li, Wen Fa Wu

研究成果: 書貢獻/報告類型會議貢獻

1 引文 斯高帕斯(Scopus)

摘要

We describe the efficiency of deoxyribonucleic acid (DNA) immobilization onto a nanowire (NW) after employing various surface cleaning methods. From surface tension measurements and fluorescence microscopy images of the silicon oxide surfaces, we determined that the effectiveness of surface cleaning using an acetone/ethanol mixture was similar to that of piranha solution (sulfuric acid/hydrogen peroxide). Thus, we employed surface cleaning with an acetone/ethanol mixture en route toward the fabrication of a series of label-free, back-gated, 60-nm nanowire field-effect transistor (NWFET) sensors for the detection of the BRAFV599E oncogene. We applied the NWFET sensor to the successful detection of the hybridization and dehybridization processes of the BRAFV599E mutation gene.

原文英語
主出版物標題INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings
頁面872-873
頁數2
DOIs
出版狀態已發佈 - 2010
對外發佈
事件2010 3rd International Nanoelectronics Conference, INEC 2010 - Hongkong, 中国
持續時間: 一月 3 2010一月 8 2010

其他

其他2010 3rd International Nanoelectronics Conference, INEC 2010
國家/地區中国
城市Hongkong
期間1/3/101/8/10

ASJC Scopus subject areas

  • 電氣與電子工程

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