Nanotechnology in the regulation of stem cell behavior

King Chuen Wu, Ching Li Tseng, Chi Chang Wu, Feng Chen Kao, Yuan Kun Tu, Edmund C So, Yang Kao Wang

研究成果: 雜誌貢獻回顧型文獻

14 引文 斯高帕斯(Scopus)

摘要

Stem cells are known for their potential to repair damaged tissues. The adhesion, growth and differentiation of stem cells are likely controlled by the surrounding microenvironment which contains both chemical and physical cues. Physical cues in the microenvironment, for example, nanotopography, were shown to play important roles in stem cell fate decisions. Thus, controlling stem cell behavior by nanoscale topography has become an important issue in stem cell biology. Nanotechnology has emerged as a new exciting field and research from this field has greatly advanced. Nanotechnology allows the manipulation of sophisticated surfaces/scaffolds which can mimic the cellular environment for regulating cellular behaviors. Thus, we summarize recent studies on nanotechnology with applications to stem cell biology, including the regulation of stem cell adhesion, growth, differentiation, tracking and imaging. Understanding the interactions of nanomaterials with stem cells may provide the knowledge to apply to cell-scaffold combinations in tissue engineering and regenerative medicine.
原文英語
文章編號054401
期刊Science and Technology of Advanced Materials
14
發行號5
DOIs
出版狀態已發佈 - 十月 2013

ASJC Scopus subject areas

  • Materials Science(all)

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