Nanotechnology in the regulation of stem cell behavior

King Chuen Wu, Ching Li Tseng, Chi Chang Wu, Feng Chen Kao, Yuan Kun Tu, Edmund C So, Yang Kao Wang

研究成果: 雜誌貢獻回顧型文獻

14 引文 (Scopus)

摘要

Stem cells are known for their potential to repair damaged tissues. The adhesion, growth and differentiation of stem cells are likely controlled by the surrounding microenvironment which contains both chemical and physical cues. Physical cues in the microenvironment, for example, nanotopography, were shown to play important roles in stem cell fate decisions. Thus, controlling stem cell behavior by nanoscale topography has become an important issue in stem cell biology. Nanotechnology has emerged as a new exciting field and research from this field has greatly advanced. Nanotechnology allows the manipulation of sophisticated surfaces/scaffolds which can mimic the cellular environment for regulating cellular behaviors. Thus, we summarize recent studies on nanotechnology with applications to stem cell biology, including the regulation of stem cell adhesion, growth, differentiation, tracking and imaging. Understanding the interactions of nanomaterials with stem cells may provide the knowledge to apply to cell-scaffold combinations in tissue engineering and regenerative medicine.
原文英語
文章編號054401
期刊Science and Technology of Advanced Materials
14
發行號5
DOIs
出版狀態已發佈 - 十月 2013

指紋

Stem cells
Nanotechnology
Cytology
Cell adhesion
Scaffolds (biology)
Tissue engineering
Nanostructured materials
Scaffolds
Topography
Repair
Adhesion
Tissue
Imaging techniques

ASJC Scopus subject areas

  • Materials Science(all)

引用此文

Nanotechnology in the regulation of stem cell behavior. / Wu, King Chuen; Tseng, Ching Li; Wu, Chi Chang; Kao, Feng Chen; Tu, Yuan Kun; C So, Edmund; Wang, Yang Kao.

於: Science and Technology of Advanced Materials, 卷 14, 編號 5, 054401, 10.2013.

研究成果: 雜誌貢獻回顧型文獻

Wu, King Chuen ; Tseng, Ching Li ; Wu, Chi Chang ; Kao, Feng Chen ; Tu, Yuan Kun ; C So, Edmund ; Wang, Yang Kao. / Nanotechnology in the regulation of stem cell behavior. 於: Science and Technology of Advanced Materials. 2013 ; 卷 14, 編號 5.
@article{7580dce4e02c429f96c8b2bf4cf2d2e7,
title = "Nanotechnology in the regulation of stem cell behavior",
abstract = "Stem cells are known for their potential to repair damaged tissues. The adhesion, growth and differentiation of stem cells are likely controlled by the surrounding microenvironment which contains both chemical and physical cues. Physical cues in the microenvironment, for example, nanotopography, were shown to play important roles in stem cell fate decisions. Thus, controlling stem cell behavior by nanoscale topography has become an important issue in stem cell biology. Nanotechnology has emerged as a new exciting field and research from this field has greatly advanced. Nanotechnology allows the manipulation of sophisticated surfaces/scaffolds which can mimic the cellular environment for regulating cellular behaviors. Thus, we summarize recent studies on nanotechnology with applications to stem cell biology, including the regulation of stem cell adhesion, growth, differentiation, tracking and imaging. Understanding the interactions of nanomaterials with stem cells may provide the knowledge to apply to cell-scaffold combinations in tissue engineering and regenerative medicine.",
keywords = "cell adhesion, differentiation, nanotechnology, nanotopography, stem cells",
author = "Wu, {King Chuen} and Tseng, {Ching Li} and Wu, {Chi Chang} and Kao, {Feng Chen} and Tu, {Yuan Kun} and {C So}, Edmund and Wang, {Yang Kao}",
year = "2013",
month = "10",
doi = "10.1088/1468-6996/14/5/054401",
language = "English",
volume = "14",
journal = "Science and Technology of Advanced Materials",
issn = "1468-6996",
publisher = "IOP Publishing Ltd.",
number = "5",

}

TY - JOUR

T1 - Nanotechnology in the regulation of stem cell behavior

AU - Wu, King Chuen

AU - Tseng, Ching Li

AU - Wu, Chi Chang

AU - Kao, Feng Chen

AU - Tu, Yuan Kun

AU - C So, Edmund

AU - Wang, Yang Kao

PY - 2013/10

Y1 - 2013/10

N2 - Stem cells are known for their potential to repair damaged tissues. The adhesion, growth and differentiation of stem cells are likely controlled by the surrounding microenvironment which contains both chemical and physical cues. Physical cues in the microenvironment, for example, nanotopography, were shown to play important roles in stem cell fate decisions. Thus, controlling stem cell behavior by nanoscale topography has become an important issue in stem cell biology. Nanotechnology has emerged as a new exciting field and research from this field has greatly advanced. Nanotechnology allows the manipulation of sophisticated surfaces/scaffolds which can mimic the cellular environment for regulating cellular behaviors. Thus, we summarize recent studies on nanotechnology with applications to stem cell biology, including the regulation of stem cell adhesion, growth, differentiation, tracking and imaging. Understanding the interactions of nanomaterials with stem cells may provide the knowledge to apply to cell-scaffold combinations in tissue engineering and regenerative medicine.

AB - Stem cells are known for their potential to repair damaged tissues. The adhesion, growth and differentiation of stem cells are likely controlled by the surrounding microenvironment which contains both chemical and physical cues. Physical cues in the microenvironment, for example, nanotopography, were shown to play important roles in stem cell fate decisions. Thus, controlling stem cell behavior by nanoscale topography has become an important issue in stem cell biology. Nanotechnology has emerged as a new exciting field and research from this field has greatly advanced. Nanotechnology allows the manipulation of sophisticated surfaces/scaffolds which can mimic the cellular environment for regulating cellular behaviors. Thus, we summarize recent studies on nanotechnology with applications to stem cell biology, including the regulation of stem cell adhesion, growth, differentiation, tracking and imaging. Understanding the interactions of nanomaterials with stem cells may provide the knowledge to apply to cell-scaffold combinations in tissue engineering and regenerative medicine.

KW - cell adhesion

KW - differentiation

KW - nanotechnology

KW - nanotopography

KW - stem cells

UR - http://www.scopus.com/inward/record.url?scp=84887035199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887035199&partnerID=8YFLogxK

U2 - 10.1088/1468-6996/14/5/054401

DO - 10.1088/1468-6996/14/5/054401

M3 - Review article

AN - SCOPUS:84887035199

VL - 14

JO - Science and Technology of Advanced Materials

JF - Science and Technology of Advanced Materials

SN - 1468-6996

IS - 5

M1 - 054401

ER -