Nanofibers used for the delivery of analgesics

Yuan Yun Tseng, Shih Jung Liu

研究成果: 雜誌貢獻文章同行評審

22 引文 斯高帕斯(Scopus)

摘要

Nanofibers are extremely advantageous for drug delivery because of their high surface area-to-volume ratios, high porosities and 3D open porous structures. Local delivery of analgesics by using nanofibers allows site-specificity and requires a lower overall drug dosage with lower adverse side effects. Different analgesics have been loaded onto various nanofibers, including those that are natural, synthetic and copolymer, for various medical applications. Analgesics can also be singly or coaxially loaded onto nanofibers to enhance clinical applications. In particular, analgesic-eluting nanofibers provide additional benefits to preventing wound adhesion and scar formation. This paper reviews current research and breakthrough discoveries on the innovative application of analgesic-loaded nanofibers that will alter the clinical therapy of pain.

原文英語
頁(從 - 到)1785-1800
頁數16
期刊Nanomedicine
10
發行號11
DOIs
出版狀態已發佈 - 6月 1 2015

ASJC Scopus subject areas

  • 材料科學(全部)
  • 生物工程
  • 生物醫學工程
  • 醫藥(雜項)
  • 發展

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