A 45-yr-old female presented with a rapidly enlarging bony tumor that was eventually identified as a Philadelphia chromosome (Ph1)-positive myeloproliferative disorder with extramedullary blastic transformation. This transformation occurred in the absence of demonstrable chronic or acute leukemic phase. She had no history of a chronic or prodromal illness in spite of a bone marrow biopsy showing myelofibrosis and liver biopsy documenting extramedullary hematopoiesis. This case represents a unique constellation of features of the myeloproliferative syndrome in which the diagnosis was obscure until special stains of the bony tumor and cytogenetic studies were performed.
|頁（從 - 到）||793-801|
|出版狀態||已發佈 - 十二月 1 1978|
ASJC Scopus subject areas
Longo, D. L., Whang-Peng, J., Jaffe, E., Triche, T. J., & Young, R. C. (1978). Myeloproliferative syndromes: A unique presentation of chronic myelogenous leukemia (CML) as a primary tumor of bone. Blood, 52(4), 793-801.