摘要
Amino acid substitutions were introduced into four conserved N-linked glycosylation sites of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein, gp41, to alter the canonical N-linked glycosylation sequences. One altered site produced a severe impairment of viral infectivity, which raises the possibility that N-linked sugars at this site may have an important role in the human immunodeficiency virus type 1 life cycle.
原文 | 英語 |
---|---|
頁(從 - 到) | 1799-1803 |
頁數 | 5 |
期刊 | Journal of Virology |
卷 | 66 |
發行號 | 3 |
DOIs |
|
出版狀態 | 已發佈 - 1992 |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology