Mutant Lines of Guinea Pig L2C Leukemia. II. Comparative Cytogenetic Studies and Banding Analyses of Normal and Leukemic Karyotypes

J. Whang Peng, E. C. Lee

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6 引文 斯高帕斯(Scopus)

摘要

Chromosomes of normal guinea pig (strain 2) cells and of cell lines derived from a spontaneously arising leukemia were analyzed in detail. All cell lines studied, LG-L2C, GH-L2C, BZ-L*C, and EN-L2C, contained one M1 marker and two X chromosomes, in addition to other chromosome abnormalities specific for each cell line. The presence of the M1 marker and the two X chromosomes confirmed that all of these leukemic cell lines are derived from one ancestral line. Comparison of the chromosome markers and immunologic characteristics of these lines revealed that possibly the gene involved in the determination of C3receptor sites is located on the terminal portion of the long arm of chromosome #2, but no other correlations could be made.
原文英語
頁(從 - 到)897-905
頁數9
期刊Journal of the National Cancer Institute
57
發行號4
DOIs
出版狀態已發佈 - 一月 1 1976
對外發佈

ASJC Scopus subject areas

  • 腫瘤科
  • 癌症研究

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