Multidisciplinary team discussion results in survival benefit for patients with stage III non-small-cell lung cancer

Hsiu Ying Hung, Yen Han Tseng, Heng Sheng Chao, Chao Hua Chiu, Wen Hu Hsu, Han Shui Hsu, Yu Chung Wu, Teh Ying Chou, Chun Ku Chen, Keng Li Lan, Yi Wei Chen, Yuan Hung Wu, Yuh Min Chen

研究成果: 雜誌貢獻文章同行評審

10 引文 斯高帕斯(Scopus)

摘要

Background The treatment for stage III non-small cell lung cancer (NSCLC) often involves multi-modality treatment. This retrospective study aimed to evaluate whether multidisciplinary team (MDT) discussion results in better patient survival. Materials and methods MDT discussion was optional before February 2016 and was actively encouraged by the MDT committee beginning February 2016. We reviewed the medical charts and computer records of patients with stage III NSCLC between January 2013 and December 2018. Results A total of 515 patients were included. The median survival of all the patients was 33.9 months (M). The median survival of patients who were treated after MDT discussion was 41.2 M and that of patients treated without MDT discussion was 25.7 M (p = 0.018). The median survival of patients treated before February 2016 was 25.7 M and that of patients treated after February 2016 was 33.9 M (p = 0.003). The median survival of patients with stage IIIA tumors and those with stage IIIB tumors was 39.4 M and 25.7 M, respectively (p = 0.141). Multivariate analysis showed that MDT or not (p<0.001), T staging (p = 0.009), performance status (p<0.001), and surgery (p = 0.016) to be significant prognostic factors. Conclusion The results of the study show that MDT discussion results in survival benefit in patients with stage III NSCLC. The MDT discussion, performance status, and if surgery was performed were independent prognostic factors for patients with stage III NSCLC.

原文英語
文章編號e0236503
期刊PLoS ONE
15
發行號10 October
DOIs
出版狀態已發佈 - 10月 2020
對外發佈

ASJC Scopus subject areas

  • 多學科

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