Multidisciplinary predialysis education decreases the incidence of dialysis and reduces mortality-a controlled cohort study based on the NKFDOQI guidelines

I. Wen Wu, Shun Yin Wang, Kuang Hung Hsu, Chin Chan Lee, Chiao Yin Sun, Chi Jen Tsai, Mai Szu Wu

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119 引文 斯高帕斯(Scopus)

摘要

Background.Observational studies have demonstrated that multidisciplinary predialysis education (MPE) improves the post-dialysis outcomes of chronic kidney disease (CKD) patients. However, the beneficial effect of MPE remains unclear in prospective controlled studies.Methods. All CKD patients who visited the outpatient nephrology clinics at two centres of the Chang Gung Memorial Hospital in 2006-07 were enrolled. The incidence of dialysis and mortality were compared between MPE recipients and non-recipients. The content of the MPE was standardized in accordance with the NKFDOQI guidelines. Prognostic factors for progression to end-stage renal disease (ESRD) and all-cause mortality were analysed by using the Cox proportional hazards model.Results. Of 573 patients, 287 received MPE. Dialysis was initiated in 13.9 and 43 of the patients in the MPE and non-MPE groups, respectively (P <0.001). The mean follow-up period was 11.7 ± 0.9 months. The overall mortality was 1.7 and 10.1 in the MPE and non-MPE groups, respectively (P <0.001). Cox regression analysis revealed that diabetes, estimated glomerular filtration rate (eGFR), high-sensitive C-reactive protein (hs-CRP) and MPE assignment were significant independent predictors for progression to ESRD. Independent prognostic factors for mortality included age, diabetes, eGFR, hs-CRP and MPE assignment. Conclusions. MPE based on the NKFDOQI guidelines may decrease the incidence of dialysis and reduce mortality in late-stage CKD patients.

原文英語
頁(從 - 到)3426-3433
頁數8
期刊Nephrology Dialysis Transplantation
24
發行號11
DOIs
出版狀態已發佈 - 十一月 2009
對外發佈Yes

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

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