摘要
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 1303-1311 |
| 頁數 | 9 |
| 期刊 | American Journal of Neuroradiology |
| 卷 | 17 |
| 發行號 | 7 |
| 出版狀態 | 已發佈 - 八月 1996 |
| 對外發佈 | Yes |
指紋
ASJC Scopus subject areas
- Clinical Neurology
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
引用此文
MR of the cerebral operculum : Abnormal opercular formation in infants and children. / Chen, Cheng Yu; Zimmerman, Robert A.; Faro, Scott; Parrish, Beth; Wang, Zhiyue; Bilaniuk, Larissa T.; Chou, Ting Ywan.
於: American Journal of Neuroradiology, 卷 17, 編號 7, 08.1996, p. 1303-1311.研究成果: 雜誌貢獻 › 文章
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TY - JOUR
T1 - MR of the cerebral operculum
T2 - Abnormal opercular formation in infants and children
AU - Chen, Cheng Yu
AU - Zimmerman, Robert A.
AU - Faro, Scott
AU - Parrish, Beth
AU - Wang, Zhiyue
AU - Bilaniuk, Larissa T.
AU - Chou, Ting Ywan
PY - 1996/8
Y1 - 1996/8
N2 - PURPOSE: To evaluate abnormalities of the cerebral operculum in infants and children and to propose the embryogenic basis of abnormal opercular formation as determined from MR imaging findings. METHODS: Eighty-six infants and children who had abnormally wide interopercular distances and/or distorted opercular topography seen on MR images were studied retrospectively. Clinically, patients presented with tonal abnormalities, macrocephaly, microcephaly, seizures, developmental delay, cerebral palsy, or facial dysmorphism. The abnormal opercula were compared with developing opercula at different stages of gestation. RESULTS: Among the 86 infants and children, two categories of opercular abnormalities were identified: an underdeveloped operculum (n = 64) and a malformed operculum (n = 22). The malformed operculum was further classified into three subtypes: nonformation of the operculum with lissencephaly (n = 1, 1%), abnormal opercular formation with pachygyria (n = 11, 13%), and nonformation or abnormal formation of the operculum without pachygyria or lissencephaly (n = 10, 12%). Two subtypes of the underdeveloped operculum were identified: an open operculum without a normal insula (n = 6, 7%) and an open operculum with a normal insula (n = 58, 67%). The five subtypes of abnormal opercular configuration showed a range of maturity that was comparable to the developing operculum at different ages. CONCLUSION: Opercular anomalies appear to follow sequentially predetermined normal steps in development. Arrest in opercular development or malformation may occur after an initial insult. MR imaging is the method of choice by which to identify these abnormalities.
AB - PURPOSE: To evaluate abnormalities of the cerebral operculum in infants and children and to propose the embryogenic basis of abnormal opercular formation as determined from MR imaging findings. METHODS: Eighty-six infants and children who had abnormally wide interopercular distances and/or distorted opercular topography seen on MR images were studied retrospectively. Clinically, patients presented with tonal abnormalities, macrocephaly, microcephaly, seizures, developmental delay, cerebral palsy, or facial dysmorphism. The abnormal opercula were compared with developing opercula at different stages of gestation. RESULTS: Among the 86 infants and children, two categories of opercular abnormalities were identified: an underdeveloped operculum (n = 64) and a malformed operculum (n = 22). The malformed operculum was further classified into three subtypes: nonformation of the operculum with lissencephaly (n = 1, 1%), abnormal opercular formation with pachygyria (n = 11, 13%), and nonformation or abnormal formation of the operculum without pachygyria or lissencephaly (n = 10, 12%). Two subtypes of the underdeveloped operculum were identified: an open operculum without a normal insula (n = 6, 7%) and an open operculum with a normal insula (n = 58, 67%). The five subtypes of abnormal opercular configuration showed a range of maturity that was comparable to the developing operculum at different ages. CONCLUSION: Opercular anomalies appear to follow sequentially predetermined normal steps in development. Arrest in opercular development or malformation may occur after an initial insult. MR imaging is the method of choice by which to identify these abnormalities.
KW - Brain, abnormalities and anomalies
KW - Brain, growth and development
KW - Brain, magnetic resonance
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M3 - Article
C2 - 8871716
AN - SCOPUS:0029798254
VL - 17
SP - 1303
EP - 1311
JO - American Journal of Neuroradiology
JF - American Journal of Neuroradiology
SN - 0195-6108
IS - 7
ER -