Molecular epidemiology of multidrug-resistant Mycobacterium tuberculosis in Eastern Taiwan

A. H. Hsu, C. B. Lin, Y. S. Lee, C. Y. Chiang, L. K. Chen, Y. S. Tsai, Jen Jyh Lee

研究成果: 雜誌貢獻文章

12 引文 (Scopus)

摘要

Taiwan initiated a multidrug-resistant tuberculosis (MDR-TB) programme in May 2007. Seventy-seven MDR-TB patients were enrolled from May 2007 to February 2009 in Eastern Taiwan. Isolates of 73 (94%) patients were available for genotyping using spoligotyping and MIRU-VNTR (mycobacterial interspersed repetitive unit-v ariable number of tandem repeats). Spoligotyping results indicated the Beijing strain as the predominant genotype (n = 48, 66%). Of the 73 isolates, 28 (38.4%) had a unique pattern and 45 (61.6%) were clustered pattern strains. Epidemiological links could be established in 21 (46.7%) of the 45 patients with a clustered pattern strain. The proportion of MDR-TB patients with a clustered pattern strain in Eastern Taiwan was high.

原文英語
頁(從 - 到)924-926
頁數3
期刊International Journal of Tuberculosis and Lung Disease
14
發行號7
出版狀態已發佈 - 2010
對外發佈Yes

指紋

Multidrug-Resistant Tuberculosis
Molecular Epidemiology
Taiwan
Mycobacterium tuberculosis
Tandem Repeat Sequences
Genotype

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases
  • Medicine(all)

引用此文

Molecular epidemiology of multidrug-resistant Mycobacterium tuberculosis in Eastern Taiwan. / Hsu, A. H.; Lin, C. B.; Lee, Y. S.; Chiang, C. Y.; Chen, L. K.; Tsai, Y. S.; Lee, Jen Jyh.

於: International Journal of Tuberculosis and Lung Disease, 卷 14, 編號 7, 2010, p. 924-926.

研究成果: 雜誌貢獻文章

Hsu, A. H. ; Lin, C. B. ; Lee, Y. S. ; Chiang, C. Y. ; Chen, L. K. ; Tsai, Y. S. ; Lee, Jen Jyh. / Molecular epidemiology of multidrug-resistant Mycobacterium tuberculosis in Eastern Taiwan. 於: International Journal of Tuberculosis and Lung Disease. 2010 ; 卷 14, 編號 7. 頁 924-926.
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abstract = "Taiwan initiated a multidrug-resistant tuberculosis (MDR-TB) programme in May 2007. Seventy-seven MDR-TB patients were enrolled from May 2007 to February 2009 in Eastern Taiwan. Isolates of 73 (94{\%}) patients were available for genotyping using spoligotyping and MIRU-VNTR (mycobacterial interspersed repetitive unit-v ariable number of tandem repeats). Spoligotyping results indicated the Beijing strain as the predominant genotype (n = 48, 66{\%}). Of the 73 isolates, 28 (38.4{\%}) had a unique pattern and 45 (61.6{\%}) were clustered pattern strains. Epidemiological links could be established in 21 (46.7{\%}) of the 45 patients with a clustered pattern strain. The proportion of MDR-TB patients with a clustered pattern strain in Eastern Taiwan was high.",
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AU - Tsai, Y. S.

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