Molecular detection of rifabutin-susceptible Mycobacterium tuberculosis

Huang Yao Chen, Ming Chih Yu, Wei Lun Huang, Mei Hua Wu, Yung Lin Chang, Chien Rai Che, Ruwen Jou

研究成果: 雜誌貢獻文章同行評審

16 引文 斯高帕斯(Scopus)

摘要

Rapid assays are still needed to detect rifabutin (RFB) susceptibility for proper tuberculosis treatment. To assess the use of the GenoType MTBDRplus assay and subsequent rpoB gene sequencing on detection of RFB susceptibility, we analyzed 800 multidrug- resistant Mycobacterium tuberculosis isolates, and 13% (104/800) were RFB susceptible. Of the 104 RFB-susceptible isolates, 71 (68.3%) isolates were rapidly identified using two molecular assays, while the remaining isolates could be determined using conventional drug-susceptibility testing according to the clinician's decision.

原文英語
頁(從 - 到)2085-2088
頁數4
期刊Journal of Clinical Microbiology
50
發行號6
DOIs
出版狀態已發佈 - 6月 2012

ASJC Scopus subject areas

  • 微生物學(醫學)

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