Molecular characterization of dengue viruses imported into Taiwan during 2003-2007: Geographic distribution and genotype shift

Pei Yun Shu, Chien Ling Su, Tsai Ling Liao, Cheng Fen Yang, Shu Fen Chang, Chien Chou Lin, Mei Chun Chang, Huai Chin Hu, Jyh Hsiung Huang

研究成果: 雜誌貢獻文章

57 引文 斯高帕斯(Scopus)

摘要

We presented our surveillance results on imported dengue cases in Taiwan during 2003-2007. A total of 542 imported dengue patients were identified. The travelers were infected in 17 countries in Southeast Asia, the Indian subcontinent, East African islands, South Pacific islands, and Central America. Most of these imported cases were infected in Southeast Asian countries. Phylogenetic analyses were conducted to examine 288 imported dengue virus (DENV) strains introduced from 13 countries. The results provide an updated view on the geographic distribution and dynamic transmission of epidemic DENV stains circulated in Southeast Asian countries. Although the geographic distributions of genotypes of DENV-3 isolated from Southeast Asian countries remain unchanged, the introductions and local expansions of epidemic DENV-1, DENV-2, and DENV-4 strains into new areas in Asia were observed. These findings highlight the importance to strengthen laboratory-based dengue surveillance for better understanding of transmission dynamics and molecular evolution of DENVs.
原文英語
頁(從 - 到)1039-1046
頁數8
期刊American Journal of Tropical Medicine and Hygiene
80
發行號6
出版狀態已發佈 - 六月 1 2009
對外發佈Yes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

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  • 引用此

    Shu, P. Y., Su, C. L., Liao, T. L., Yang, C. F., Chang, S. F., Lin, C. C., Chang, M. C., Hu, H. C., & Huang, J. H. (2009). Molecular characterization of dengue viruses imported into Taiwan during 2003-2007: Geographic distribution and genotype shift. American Journal of Tropical Medicine and Hygiene, 80(6), 1039-1046.