MicroRNAs in atherosclerosis

Ku Chung Chen, Suh Hang Hank Juo

研究成果: 雜誌貢獻文章同行評審

36 引文 斯高帕斯(Scopus)

摘要

MicroRNAs are endogenously expressed small noncoding RNAs that regulate gene expression at the post-transcriptional level. MicroRNAs have emerged as key regulators of several physiological and pathophysiological processes in the cardiovascular system. Aberrant expression of microRNAs has been implicated in the pathophysiological processes underlying the development of atherosclerosis and cardiovascular disease, including change in endothelial function, vascular smooth muscle cell proliferation and migration, macrophage function, and foam cell formation. In this review, we summarize the recent data showing the roles of microRNAs in cell studies, studies on atherosclerotic mice, and human studies.

原文英語
頁(從 - 到)631-640
頁數10
期刊Kaohsiung Journal of Medical Sciences
28
發行號12
DOIs
出版狀態已發佈 - 十二月 2012
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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