Microbial transformations of Isocupressic acid

Shwu Jiuan Lin, J. P N Rosazza

研究成果: 雜誌貢獻文章同行評審

19 引文 斯高帕斯(Scopus)

摘要

Microbial transformations of the labdane-diterpene isocupressic acid (1) with different microorganisms yielded several oxygenated metabolites that were isolated and characterized by MS and NMR spectroscopic analyses. Nocardia aurantia (ATCC 12674) catalyzed the cleavage of the 13,14-double bond to yield a new nor-labdane metabolite, 2. Cunninghamella elegans (-) (NRRL 1393) gave 7β-hydroxyisocupressic acid (3) and labda-7,13(E)-diene- 6β,15,17-triol-19-oic acid (4), and Mucor mucedo (ATCC 20094) gave 2α- hydroxyisocupressic acid (5) and labda-8(17),14-diene-2α,13-diol-19-oic acid (6).

原文英語
頁(從 - 到)922-926
頁數5
期刊Journal of Natural Products
61
發行號7
DOIs
出版狀態已發佈 - 七月 1998
對外發佈Yes

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

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