Micro diffuser-type movement inversion sorter for high-efficient sperm sorting

Yu Nan Lin, Peng Chun Chen, Ren Guei Wu, Li Chern Pan, Fan Gang Tseng

研究成果: 書貢獻/報告類型會議貢獻

4 引文 斯高帕斯(Scopus)

摘要

In this study, we propose a microfluidic device with a diffuser type chamber to differentiate the sperm velocity by gradually lowering down the flow speed in diffuser by gradually increasing the width of the channel. When the sperms' moving speed match the flow speed, the sperms tend to have the ability to flow against the stream, thus separating the sperms at different specific positions along the diffuser according to their motility becomes gentle and fast. Most of the motile sperm will stay in the expanding area and the non-motile sperms will drift to outlet. Different from the previous study we proposed in IEEE NEMS, 2012, here we have three improvements: (1) Sperms can be separated in more detailed quality level. (2) Sperm will be more activated by passing through a dumb bell area than by the traditional methods. (3) The space in the device can accumulate large amount of sperms (∼millions).

原文英語
主出版物標題8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013
頁面1058-1061
頁數4
DOIs
出版狀態已發佈 - 2013
對外發佈
事件8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013 - Suzhou, 中国
持續時間: 四月 7 2013四月 10 2013

其他

其他8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013
國家/地區中国
城市Suzhou
期間4/7/134/10/13

ASJC Scopus subject areas

  • 生物化學、遺傳與分子生物學(雜項)
  • 生物技術

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