Mesoporous silica nanoparticles as nanocarriers

Si Han Wu, Yann Hung, Chung Yuan Mou

研究成果: 雜誌貢獻文章

235 引文 斯高帕斯(Scopus)

摘要

Modern nanomedicine aims at delivering drugs or cells specifically to defective cells; therefore, this calls for developing multifunctional nanocarriers for drug delivery and cell-tracking. Mesoporous silica nanoparticles (MSNs) are well suited for this task. In this feature article, we highlight the strategies in the synthesis and functionalization of small, uniform and colloidal stable MSNs. We then discuss cell uptake of MSNs and tracking cells, as both aspects are closely related to the efficacy of drug delivery and theranostics. Some examples of stimulated drug delivery are described. For application considerations, toxicity and pharmacokinetics are critical issues and in vivo studies are summarized.

原文英語
頁(從 - 到)9972-9985
頁數14
期刊Chemical Communications
47
發行號36
DOIs
出版狀態已發佈 - 九月 28 2011
對外發佈Yes

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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