Mesenchymal stem cell attachment to peptide density gradients on porous silicon generated by electrografting

Lauren R. Clements; Peng Yuan Wang; Frances Harding; Wei Bor Tsai; Helmut Thissen; Nicolas H. Voelcker

doi:10.1002/pssa.201000320

Mesenchymal stem cell attachment to peptide density gradients on porous silicon generated by electrografting

Lauren R. Clements, Peng Yuan Wang, Frances Harding, Wei Bor Tsai, Helmut Thissen, Nicolas H. Voelcker

研究成果: 雜誌貢獻 › 文章

27 引文斯高帕斯（Scopus）

摘要

Chemical gradients of ethyl-6-bromohexanoate (EBH) were generated over porous silicon (pSi) substrates via electrochemical attachment. Immobilised ester moieties were hydrolysed and activated to produce a gradient of functional carboxylic acid groups. After subsequent immobilisation of cyclic RGD (cRGD), the surfaces were used to screen the extent of rat mesenchymal stem cell (MSC) attachment. Mapping of surface chemistry was carried out by means of infrared microscopy and X-ray photoelectron spectroscopy (XPS). MSC culture studies showed that short-term cell attachment responded to the cRGD density present on the gradient surface.

原文	英語
頁（從 - 到）	1440-1445
頁數	6
期刊	Physica Status Solidi (A) Applications and Materials Science
卷	208
發行號	6
DOIs	https://doi.org/10.1002/pssa.201000320
出版狀態	已發佈 - 六月 2011
對外發佈	Yes

指紋

ASJC Scopus subject areas

Electrical and Electronic Engineering
Electronic, Optical and Magnetic Materials
Materials Chemistry
Condensed Matter Physics
Surfaces and Interfaces
Surfaces, Coatings and Films

引用此

Clements, L. R., Wang, P. Y., Harding, F., Tsai, W. B., Thissen, H., & Voelcker, N. H. (2011). Mesenchymal stem cell attachment to peptide density gradients on porous silicon generated by electrografting. Physica Status Solidi (A) Applications and Materials Science, 208(6), 1440-1445. https://doi.org/10.1002/pssa.201000320

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存取文件

10.1002/pssa.201000320