摘要
Chemical gradients of ethyl-6-bromohexanoate (EBH) were generated over porous silicon (pSi) substrates via electrochemical attachment. Immobilised ester moieties were hydrolysed and activated to produce a gradient of functional carboxylic acid groups. After subsequent immobilisation of cyclic RGD (cRGD), the surfaces were used to screen the extent of rat mesenchymal stem cell (MSC) attachment. Mapping of surface chemistry was carried out by means of infrared microscopy and X-ray photoelectron spectroscopy (XPS). MSC culture studies showed that short-term cell attachment responded to the cRGD density present on the gradient surface.
原文 | 英語 |
---|---|
頁(從 - 到) | 1440-1445 |
頁數 | 6 |
期刊 | Physica Status Solidi (A) Applications and Materials Science |
卷 | 208 |
發行號 | 6 |
DOIs | |
出版狀態 | 已發佈 - 6月 2011 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 電氣與電子工程
- 電子、光磁材料
- 材料化學
- 凝聚態物理學
- 表面和介面
- 表面、塗料和薄膜