MeDIP-on-chip for methylation profiling

研究成果: 書貢獻/報告類型章節

1 引文 (Scopus)

摘要

DNA methylation is an important regulatory step in gene expression. Knowledge of the alterations in DNA methylation at a whole genome scale improves our understanding of gene regulation and potential correlations with biological events or disease progression. Methylated DNA immunoprecipitation (MeDIP) uses an antibody that efficiently enriches methylated DNA fragments for downstream locus-specific or genome-wide analyses. MeDIP-on-Chip uses the MeDIP approach in combination with a tiling array for the investigation of genome-wide DNA methylation patterns (or DNA methylomics). The following protocol describes the application of MeDIP to the hybridization of DNA microarrays and data analysis.
原文英語
主出版物標題Cervical Cancer: Methods and Protocols
發行者Springer New York
頁面281-290
頁數10
ISBN(列印)9781493920136, 9781493920129
DOIs
出版狀態已發佈 - 十月 27 2014

指紋

Immunoprecipitation
Methylation
DNA
DNA Methylation
Genome
Microarray Analysis
Oligonucleotide Array Sequence Analysis
Disease Progression
Gene Expression
Antibodies
Genes

ASJC Scopus subject areas

  • Medicine(all)

引用此文

Hsu, Y. W., Huang, R. L., & Lai, H. C. (2014). MeDIP-on-chip for methylation profiling. 於 Cervical Cancer: Methods and Protocols (頁 281-290). Springer New York. https://doi.org/10.1007/978-1-4939-2013-6_21

MeDIP-on-chip for methylation profiling. / Hsu, Yaw Wen; Huang, Rui Lan; Lai, Hung Cheng.

Cervical Cancer: Methods and Protocols. Springer New York, 2014. p. 281-290.

研究成果: 書貢獻/報告類型章節

Hsu, YW, Huang, RL & Lai, HC 2014, MeDIP-on-chip for methylation profiling. 於 Cervical Cancer: Methods and Protocols. Springer New York, 頁 281-290. https://doi.org/10.1007/978-1-4939-2013-6_21
Hsu YW, Huang RL, Lai HC. MeDIP-on-chip for methylation profiling. 於 Cervical Cancer: Methods and Protocols. Springer New York. 2014. p. 281-290 https://doi.org/10.1007/978-1-4939-2013-6_21
Hsu, Yaw Wen ; Huang, Rui Lan ; Lai, Hung Cheng. / MeDIP-on-chip for methylation profiling. Cervical Cancer: Methods and Protocols. Springer New York, 2014. 頁 281-290
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