Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million

C. H. Tseng, C. C. Liao, C. M. Kuo, F. C. Sung, D. P H Hsieh, C. H. Tsai

研究成果: 雜誌貢獻文章

28 引文 (Scopus)

摘要

Background: Carpal tunnel syndrome (CTS), with unclear etiology, is the most common entrapment neuropathy. Its occurrence is related to lots of medical and non-medical conditions with uncertain causality. With a large population, we characterized selected demographical and clinical factors to add more information on CTS-correlated factors and new insight into future CTS prevention. Methods: A national insurance claim dataset of one million enrollees in Taiwan was used to identify 15802 patients with CTS and 31604 randomly selected controls, during a period of 7years starting 1 January 2000. Statistical association with CTS was determined for five sociodemographic and nine medical factors. Results: Patients were predominantly women (65.6% vs. 47.7% in the control group) and older (40 and above, 62.6% vs. 36.2%). Rheumatoid arthritis was found to be the most significant comorbidity associated with CTS, followed by gout, hypertension, diabetes, obesity, uremia, and acromegaly. For younger group age ≤39, the association of these comorbidities was stronger, and hypothyroidism and vitamin B 6 deficiency were additional comorbidities. Aging appears to reduce the relative impact of the diseases commonly associated with CTS as the possible risk factors. Conclusions: Identification of the CTS correlates in younger group would be of greater value in timely detection and treatment for these diseases. Correcting these disorders may aid in removing possible causes of CTS. This is the first report on the effect of aging on probable CTS risk factors. How factors associated with aging contribute to the development of CTS remains to be determined.

原文英語
頁(從 - 到)91-97
頁數7
期刊European Journal of Neurology
19
發行號1
DOIs
出版狀態已發佈 - 一月 2012
對外發佈Yes

指紋

Carpal Tunnel Syndrome
Taiwan
Comorbidity
Vitamin B 6 Deficiency
Nerve Compression Syndromes
Acromegaly
Gout
Uremia
Hypothyroidism
Insurance
Causality
Rheumatoid Arthritis
Age Groups
Obesity
Hypertension

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

引用此文

Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million. / Tseng, C. H.; Liao, C. C.; Kuo, C. M.; Sung, F. C.; Hsieh, D. P H; Tsai, C. H.

於: European Journal of Neurology, 卷 19, 編號 1, 01.2012, p. 91-97.

研究成果: 雜誌貢獻文章

Tseng, C. H. ; Liao, C. C. ; Kuo, C. M. ; Sung, F. C. ; Hsieh, D. P H ; Tsai, C. H. / Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million. 於: European Journal of Neurology. 2012 ; 卷 19, 編號 1. 頁 91-97.
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abstract = "Background: Carpal tunnel syndrome (CTS), with unclear etiology, is the most common entrapment neuropathy. Its occurrence is related to lots of medical and non-medical conditions with uncertain causality. With a large population, we characterized selected demographical and clinical factors to add more information on CTS-correlated factors and new insight into future CTS prevention. Methods: A national insurance claim dataset of one million enrollees in Taiwan was used to identify 15802 patients with CTS and 31604 randomly selected controls, during a period of 7years starting 1 January 2000. Statistical association with CTS was determined for five sociodemographic and nine medical factors. Results: Patients were predominantly women (65.6{\%} vs. 47.7{\%} in the control group) and older (40 and above, 62.6{\%} vs. 36.2{\%}). Rheumatoid arthritis was found to be the most significant comorbidity associated with CTS, followed by gout, hypertension, diabetes, obesity, uremia, and acromegaly. For younger group age ≤39, the association of these comorbidities was stronger, and hypothyroidism and vitamin B 6 deficiency were additional comorbidities. Aging appears to reduce the relative impact of the diseases commonly associated with CTS as the possible risk factors. Conclusions: Identification of the CTS correlates in younger group would be of greater value in timely detection and treatment for these diseases. Correcting these disorders may aid in removing possible causes of CTS. This is the first report on the effect of aging on probable CTS risk factors. How factors associated with aging contribute to the development of CTS remains to be determined.",
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