Mechanical unfolding and refolding of proteins: An off-lattice model study

Feng Yin Li; Jian Min Yuan; Chung Yuan Mou

doi:10.1103/PhysRevE.63.021905

Mechanical unfolding and refolding of proteins: An off-lattice model study

Feng Yin Li, Jian Min Yuan, Chung Yuan Mou

研究成果: 雜誌貢獻 › 文章 › 同行評審

18 引文斯高帕斯（Scopus）

摘要

Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.

原文	英語
期刊	Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
卷	63
發行號	2
DOIs	https://doi.org/10.1103/PhysRevE.63.021905
出版狀態	已發佈 - 2001
對外發佈	是

ASJC Scopus subject areas

統計與非線性物理學
統計與概率
凝聚態物理學

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10.1103/PhysRevE.63.021905

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Mechanical unfolding and refolding of proteins: An off-lattice model study

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ASJC Scopus subject areas

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