Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.
|期刊||Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics|
|出版狀態||已發佈 - 2001|
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