Mathematical explanations for alterations of heart-rate variability after autonomic blockade and during exercise

H. W. Chiu, T. Kao

研究成果: 書貢獻/報告類型會議貢獻

摘要

Some inconsistent results occurred in the assessment of autonomic activity using the spectral analysis of heart rate variability (HRV) in some physiological and pharmacological conditions. In this study, we attempted to clarify the alterations of HRV after sympathetic blockade, vagal blockade and during exercise using a mathematical model. The autonomic activity in normal condition was assumed first according to some experimental evidences. Then autonomic activities after sympathetic blockade, vagal blockade and during exercise were appropriately set accordingly for simulations. Results showed that the alternations of HRV in these conditions were similar to those in actual measurements. We found that the mean heartbeat interval played an important role in the alterations of HRV in these conditions. The inconsistencies for HRV analysis could be explained mathematically by taking the mean heartbeat interval into account.
原文英語
主出版物標題Computers in Cardiology
發行者IEEE
頁面457-460
頁數4
出版狀態已發佈 - 2000

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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