Manipulations of core temperatures in ischemia-reperfusion lung injury in rabbits

Hung Chang, Kun Lun Huang, Min Hui Li, Ching Wang Hsu, Shih Hung Tsai, Shi Jye Chu

研究成果: 雜誌貢獻文章

4 引文 (Scopus)

摘要

The present study was designed to determine the effect of various core temperatures on acute lung injury induced by ischemia-reperfusion (I/R) in our isolated rabbit lung model. Typical acute lung injury was successfully induced by 30 min of ischemia followed by 90 min of reperfusion observation. The I/R elicited a significant increase in pulmonary arterial pressure, microvascular permeability (measured by using the capillary filtration coefficient, Kfc), ΔKfc ratio, lung weight gain and the protein concentration of the bronchoalveolar lavage fluid. Mild hypothermia significantly attenuated acute lung injury induced by I/R, all parameters having decreased significantly (p

原文英語
頁(從 - 到)285-291
頁數7
期刊Pulmonary Pharmacology and Therapeutics
21
發行號2
DOIs
出版狀態已發佈 - 四月 2008
對外發佈Yes

指紋

Hypothermia
Lung Injury
Reperfusion Injury
Reperfusion
Acute Lung Injury
Ischemia
Rabbits
Temperature
Fluids
Lung
Proteins
Bronchoalveolar Lavage Fluid
Capillary Permeability
Weight Gain
Arterial Pressure
Observation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Pharmacology

引用此文

Manipulations of core temperatures in ischemia-reperfusion lung injury in rabbits. / Chang, Hung; Huang, Kun Lun; Li, Min Hui; Hsu, Ching Wang; Tsai, Shih Hung; Chu, Shi Jye.

於: Pulmonary Pharmacology and Therapeutics, 卷 21, 編號 2, 04.2008, p. 285-291.

研究成果: 雜誌貢獻文章

Chang, Hung ; Huang, Kun Lun ; Li, Min Hui ; Hsu, Ching Wang ; Tsai, Shih Hung ; Chu, Shi Jye. / Manipulations of core temperatures in ischemia-reperfusion lung injury in rabbits. 於: Pulmonary Pharmacology and Therapeutics. 2008 ; 卷 21, 編號 2. 頁 285-291.
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