Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screening

Laszlo Tabar, Ming Fang Yen, Bedrich Vitak, Hsiu Hsi Tony Chen, Robert A. Smith, Stephen W. Duffy

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550 引文 斯高帕斯(Scopus)

摘要

Background: The long term effect of mammographic service screening is not well established. We aimed to assess the long-term effect of mammographic screening on death from breast cancer, taking into account potential biases from self-selection, changes in breast cancer incidence, and classification of cause of death. Methods: We compared deaths from breast cancer diagnosed in the 20 years before screening was introduced (1958-77) with those from breast cancer diagnosed in the 20 years after the introduction of screening (1978-97) in two Swedish counties, in 210 000 women aged 20-69 years. We also compared deaths from all cancers and from all causes in patients diagnosed with breast cancer in the 20 years before and after screening was introduced. In the analysis, data were stratified into age-groups invited for screening (40-69 years) and not invited (20-39 years), and by whether or not the women had actually received screening. We also analysed mortality for the 40-49-year age-group separately. Findings: The unadjusted risk of death from breast cancer dropped significantly in the second screening period compared with the first in women aged 40-69 years (relative risk [RR] 0.77 [95% CI 0.7-0.85]; p
原文英語
頁(從 - 到)1405-1410
頁數6
期刊The Lancet
361
發行號9367
DOIs
出版狀態已發佈 - 四月 26 2003
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

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