We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine
Hwu, Y. M., Li, S. H., Lee, R. K. K., Lin, M. H., Tsai, Y. H., & Tsai, T-S. (2009). Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells. Fertility and Sterility, 92(6), 2065-2068. https://doi.org/10.1016/j.fertnstert.2009.05.064