Low temperature decreased tension in isolated hypertrophic human nasal mucosa

Yueng Hsiang Chu, Chin Chen Wu, Chuan Hsiang Kao, Hsing Won Wang

研究成果: 雜誌貢獻文章同行評審

9 引文 斯高帕斯(Scopus)

摘要

Background: The purpose of this study was to evaluate the effect of low temperature on basal tension in isolated hypertrophic human nasal mucosa with or without α 1-agonist stimulation. Methods: A tissue bath for isolated nasal mucosa was used. Tension in strips of human turbinate mucosa that were untreated and treated with an α 1-adrenoreceptor agonist, methoxamine (10 μM), was recorded continuously in a stepwise manner in temperatures that varied from 37 to 10°C. Results: The changes of tension in the human nasal mucosa were found to be temperature-dependent in both untreated and treated tissues, with tension decreasing to 48.6% at 10°C in comparison with 100% at 37°C in the untreated group, the presence of methoxamine (10 μM) had minimal effect. Conclusion: Low temperature induced a rapid and reproducible relaxation in isolated hypertrophic human nasal mucosa that was not affected by the presence of the α 1-agonist methoxamine (10 μM).

原文英語
頁(從 - 到)84-86
頁數3
期刊American Journal of Rhinology
20
發行號1
出版狀態已發佈 - 一月 2006
對外發佈

ASJC Scopus subject areas

  • 耳鼻咽喉科

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