Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats: Influence of aging and hypertension

J. T. Lee, H. L. Liu, J. T. Yang, S. T. Yang, J. R. Lin, T. H. Lee

研究成果: 雜誌貢獻文章

6 引文 (Scopus)

摘要

Our previous study has shown that aging and hypertension may alter apparent diffusion coefficient (ADC) and cerebral blood flow (CBF) and increase ischemic susceptibility in the non-ischemic rat brain. The present study wishes to further investigate whether aging and hypertension may influence cerebral diffusion/perfusion and increase ischemic susceptibility in the ischemic brain. Brain magnetic resonance (MR) imaging was examined 1. day before and 1 and 7. days after bilateral common carotid artery occlusion. Young and middle-aged normotensive Wistar-Kyoto rats and young and middle-aged spontaneously hypertensive rats (SHRs) were studied. Infarction occurred mainly in the parietal cortex and was larger in middle-aged SHRs than the other three groups (P

原文英語
頁(從 - 到)31-40
頁數10
期刊Neuroscience
257
DOIs
出版狀態已發佈 - 一月 17 2014

指紋

Magnetic Resonance Imaging
Inbred SHR Rats
Hypertension
Cerebrovascular Circulation
Brain
Parietal Lobe
Inbred WKY Rats
Common Carotid Artery
Infarction
Perfusion

ASJC Scopus subject areas

  • Neuroscience(all)

引用此文

Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats : Influence of aging and hypertension. / Lee, J. T.; Liu, H. L.; Yang, J. T.; Yang, S. T.; Lin, J. R.; Lee, T. H.

於: Neuroscience, 卷 257, 17.01.2014, p. 31-40.

研究成果: 雜誌貢獻文章

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AU - Yang, S. T.

AU - Lin, J. R.

AU - Lee, T. H.

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