Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats

Influence of aging and hypertension

J. T. Lee, H. L. Liu, J. T. Yang, S. T. Yang, J. R. Lin, T. H. Lee

研究成果: 雜誌貢獻文章

6 引文 (Scopus)

摘要

Our previous study has shown that aging and hypertension may alter apparent diffusion coefficient (ADC) and cerebral blood flow (CBF) and increase ischemic susceptibility in the non-ischemic rat brain. The present study wishes to further investigate whether aging and hypertension may influence cerebral diffusion/perfusion and increase ischemic susceptibility in the ischemic brain. Brain magnetic resonance (MR) imaging was examined 1. day before and 1 and 7. days after bilateral common carotid artery occlusion. Young and middle-aged normotensive Wistar-Kyoto rats and young and middle-aged spontaneously hypertensive rats (SHRs) were studied. Infarction occurred mainly in the parietal cortex and was larger in middle-aged SHRs than the other three groups (P

原文英語
頁(從 - 到)31-40
頁數10
期刊Neuroscience
257
DOIs
出版狀態已發佈 - 一月 17 2014

指紋

Magnetic Resonance Imaging
Inbred SHR Rats
Hypertension
Cerebrovascular Circulation
Brain
Parietal Lobe
Inbred WKY Rats
Common Carotid Artery
Infarction
Perfusion

ASJC Scopus subject areas

  • Neuroscience(all)

引用此文

Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats : Influence of aging and hypertension. / Lee, J. T.; Liu, H. L.; Yang, J. T.; Yang, S. T.; Lin, J. R.; Lee, T. H.

於: Neuroscience, 卷 257, 17.01.2014, p. 31-40.

研究成果: 雜誌貢獻文章

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AU - Yang, S. T.

AU - Lin, J. R.

AU - Lee, T. H.

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KW - Perfusion-weighted MRI

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